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KMID : 0616120160470030204
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Korean Journal of Pharmacognosy
2016 Volume.47 No. 3 p.204 ~ p.210
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Chemical Constituents from the Stems of Lagerstroemia indica and Their Anti-oxidant Effect
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Woo Kyeong-Wan
Sim Mi-Ok
Park Jong-Eel
Kim Min-Suk
Suh Won-Se
Cho Hyun-Woo
Kwon Hak-Cheol
Park Jong-Cheol
Lee Kang-Ro
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Abstract
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Phytochemical investigation of the 80% MeOH extract from the stems of Lagerstroemia indica resulted in the isolation of eighteen compounds; four norsesquiterpenes, fourteen phenolic derivatives. Their chemical structures were characterized by spectroscopic methods to be tachioside (1), isotachioside (2), 2,4,6-trimethoxyphenyl b-D-glucopyranoside (3), gallic acid 4-methyl ether (4), protocatechuic acid (5), gallic acid (6), vanillic acid (7), vanillin (8), 2-methoxy-5-hydroxymethyl-phenyl-1-O-(6''-galloyl)-b-D-glucopyranoside (9), 2,4,6-trimethoxyphenol-1-O-b-D-(6'-O-galloyl)-glucopyranoside (10), 4-hydroxy-3-methoxyphenyl-1-O-(6'-O-galloyl)-b-D-glucopyranoside (11), vomifoliol (12), vomifoliol 9-O-b-D-glucopyranoside (13), 6R,?9R-?3-?oxo-?α-?ionol-?9-?O-?b-?D-?glucopyranoside (14), dihydrophaseic acid 4'-O-b-D-glucopyranoside (15), b-hydroxypropiovanillone 3-O-b-D-glucopyranoside (16), myrciaphenone A (17), and coumaric acid (18). Compounds 1-5 and 7-18 were isolated for the first time from this plant. Compounds 1-18 were investigated for their antioxidant properties using DPPH and ABTS radical scavenging capacity assay, Fe2+ chelating, and FRAP assay. It was found that 4, 6, and 11 possessed the highest antioxidant capacities.
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KEYWORD
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Lythraceae, Lagerstroemia indica, Norsesquiterpene, Phenol, Anti-oxidant effect
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